The Hidden Science: How Spinal Manipulation Interacts with Your Immune System

February 08, 2026

Ever wondered what's really happening inside your body during a chiropractic adjustment? When you get an adjustment, you're triggering an intricate network of signals between your nervous system, immune system, and musculoskeletal structures—connections that modern science is just beginning to unravel. Yorkville Chiropractic and Wellness Centre is happy to share this chiropractic research news with you.

YOUR BODY'S INTERNAL COMMUNICATION NETWORK

Picture your nervous system and immune cells as partners in continual communication, coordinating their responses to keep your body functioning at its best. As Dr. Taams explains in her research on neuroimmune interactions, your nervous and immune systems are deeply intertwined—they're perpetually influencing one another, coordinating responses to keep you healthy and functioning at your peak. (1) A goal of chiropractic care here at Yorkville Chiropractic and Wellness Centre.

THE MECHANICAL MESSAGE

When you undergo spinal manipulation, you're not just having bones moved around —you're sending signals throughout your body. Recent groundbreaking research by Lewis and colleagues shares that these "mechano-responsive" signals affect both bone and joint tissues in notable ways. (2) The controlled pressure applied during manipulation sends signals that your neuroimmune system can interpret, potentially dampening inflammation, changing pain pathways, and boosting tissue recovery.

REAL-WORLD IMPLICATIONS

So what's the practical takeaway? Lutke Schipholt and her research team emphasize that understanding these neuroimmune interactions is vital for treating musculoskeletal conditions effectively. When chiropractors like yours at Yorkville Chiropractic and Wellness Centre apply specific manipulations, we're potentially modulating your immune responses at the site of injury or dysfunction—going beyond symptom relief to target the root inflammatory mechanisms. (3) This explains why many chiropractic clients report benefits beyond pain relief, including better mobility, reduced stiffness, and even better overall wellness. Your chiropractic spinal manipulation at Yorkville Chiropractic and Wellness Centre isn't just moving something back into place; it could well be initiating a cascade of beneficial biological responses throughout interconnected body systems.

THE BOTTOM LINE

The science is exploring and reporting on what many chiropractic patients have experienced firsthand: spinal manipulation works through multiple pathways simultaneously. By understanding how mechanical forces influence neuroimmune cross-talk, we're gaining deeper insight into why chiropractic care can be such an effective approach for various musculoskeletal conditions.

CONTACT Yorkville Chiropractic and Wellness Centre

Listen to this PODCAST with Dr. James Cox on The Back Doctors Podcast with Dr. Michael Johnson as he illustrates the interaction of the immune system further and the benefit of The Cox® Technic System of Spinal Pain Management for spine pain patients.

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